Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 12/20 | 0.32 |
| ▸ | DRD2 | P14416 | 9/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076092 | 0.81 | HTR1D (0.38) | HTR1DHTR1BDRD3DRD2HTR1A | |
| SCHEMBL11076941 | 0.78 | HTR1D (0.40) | HTR1DHTR1BDRD3DRD2HTR1A | |
| SCHEMBL11071936 | 0.78 | SLC6A4 (0.39) | DRD3DRD2OPRM1 | |
| SCHEMBL11069827 | 0.76 | GRIN2B (0.42) | DRD3DRD2OPRM1CYP2D6 | |
| SCHEMBL11076134 | 0.74 | HTR1D (0.38) | HTR1DHTR1BHTR1AOPRM1OPRD1 | |
| SCHEMBL11076865 | 0.74 | HTR1D (0.36) | HTR1DHTR1BDRD3DRD2HTR1A | |
| SCHEMBL11077463 | 0.72 | OPRM1 (0.46) | HTR1DDRD3DRD2HTR1AOPRM1 | |
| SCHEMBL11075002 | 0.71 | HTR1D (0.36) | HTR1DHTR1BHTR1AOPRM1ALDH1A1 | |
| SCHEMBL11071916 | 0.70 | OPRM1 (0.38) | OPRM1CYP2D6TSHR | |
| SCHEMBL11072284 | 0.69 | PARP1 (0.33) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |