Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14541835 | 0.81 | MGAM (0.47) | GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7383382 | 0.77 | PIN1 (0.49) | PIN1MMP8LMNAMDM4MAPT | |
| SCHEMBL8998830 | 0.76 | PIN1 (0.45) | PIN1MMP8LMNAMDM4MAPT | |
| SCHEMBL4804225 | 0.75 | ALDH1A1 (0.56) | PIN1MMP8LMNAMDM4MAPT | |
| SCHEMBL18979501 | 0.75 | PIN1 (0.50) | PIN1MMP8LMNAMDM4MAPT | |
| SCHEMBL18979500 | 0.75 | PIN1 (0.50) | PIN1MMP8LMNAMDM4MAPT | |
| SCHEMBL29688898 | 0.75 | PIN1 (0.50) | PIN1MMP8LMNAMDM4MAPT | |
| SCHEMBL2993639 | 0.75 | PIN1 (0.50) | PIN1MMP8LMNAMDM4MAPT | |
| SCHEMBL17857575 | 0.74 | POLB (0.47) | PIN1MMP8LMNAMDM4MAPT | |
| SCHEMBL6773107 | 0.74 | POLB (0.47) | PIN1MMP8LMNAMDM4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435322-A | Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-03-06 | — | — | US | disclosed |