Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998946 | 0.86 | MMP8 (0.43) | PIN1MMP8LMNAALDH1A1MDM4 | |
| SCHEMBL11506989 | 0.81 | CYP1A2 (0.41) | PIN1MMP8LMNAALDH1A1CYP26A1 | |
| SCHEMBL2993639 | 0.81 | PIN1 (0.50) | PIN1MMP8LMNAALDH1A1MDM4 | |
| SCHEMBL15419570 | 0.80 | PIN1 (0.49) | PIN1MMP8LMNAALDH1A1MDM4 | |
| SCHEMBL5084136 | 0.79 | LMNA (0.55) | PIN1MMP8LMNAALDH1A1TSHR | |
| SCHEMBL11069746 | 0.76 | PIN1 (0.49) | PIN1MMP8LMNAALDH1A1MDM4 | |
| SCHEMBL15489465 | 0.76 | PIN1 (0.45) | PIN1MMP8LMNAALDH1A1MDM4 | |
| SCHEMBL14826292 | 0.75 | KCNN4 (0.50) | ALDH1A1CYP26A1MAPTTSHR | |
| SCHEMBL5972776 | 0.75 | ALDH1A1 (0.46) | PIN1MMP8LMNAALDH1A1MDM4 | |
| SCHEMBL8672395 | 0.74 | PIN1 (0.46) | PIN1MMP8LMNAALDH1A1MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554624-A | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS | J. URIACH & CIA. (ES) | 1996-09-10 | — | — | US | disclosed |
| EP-0669333-A1 | New imidazopyridine derivatives as angiotensin II antagonists | J. URIACH & CIA. S.A. (ES) | 1995-08-30 | — | — | EP | disclosed |