Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | MDM4 | O15151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11125586 | 0.79 | LMNA (0.48) | MMP8MDM4LMNAMAPTMDM2 | |
| SCHEMBL29580959 | 0.78 | MMP8 (0.54) | MMP8SMN1; SMN2PIN1KMT2AMEN1 | |
| SCHEMBL8231046 | 0.77 | TDP1 (0.52) | MMP8MDM4LMNAMAPTMDM2 | |
| SCHEMBL13506014 | 0.77 | LMNA (0.60) | MMP8MDM4LMNAMAPTMDM2 | |
| SCHEMBL7966874 | 0.77 | MMP8 (0.56) | MMP8MDM4LMNAMAPTMDM2 | |
| SCHEMBL29063435 | 0.76 | MDM4 (0.46) | MMP8MDM4LMNAMAPTMDM2 | |
| SCHEMBL266419 | 0.76 | MMP8 (0.74) | MMP8SMN1; SMN2PIN1KMT2ATSHR | |
| SCHEMBL2310025 | 0.76 | LMNA (0.62) | MMP8LMNASMN1; SMN2PIN1KMT2A | |
| SCHEMBL5728738 | 0.76 | KMT2A (0.64) | MMP8SMN1; SMN2PIN1KMT2ATSHR | |
| SCHEMBL4857780 | 0.75 | LMNA (0.45) | MMP8MDM4LMNAMAPTMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435322-A | Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-03-06 | — | — | US | disclosed |