Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2310025 | 0.81 | LMNA (0.62) | MMP8CYP3A4CYP2D6ALDH1A1LMNA | |
| SCHEMBL7434604 | 0.79 | CYP3A4 (0.53) | MMP8CYP3A4CYP2C19CYP2D6MAPT | |
| SCHEMBL1814609 | 0.79 | MMP8 (0.58) | MMP8CYP3A4CYP2C19CYP2D6MAPT | |
| SCHEMBL5784044 | 0.77 | SMN1; SMN2 (0.55) | MMP8ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11069749 | 0.77 | MMP8 (0.55) | MMP8MAPTLMNATSHRMEN1 | |
| SCHEMBL11443834 | 0.76 | CYP3A4 (0.64) | MMP8CYP3A4CYP2C19CYP2D6KDM4E | |
| SCHEMBL21400347 | 0.76 | POLB (0.62) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7104115 | 0.76 | MMP8 (0.56) | MMP8CYP2C19ALDH1A1CYP2C9LMNA | |
| SCHEMBL7104119 | 0.76 | MMP8 (0.56) | MMP8CYP2C19ALDH1A1CYP2C9LMNA | |
| Toluene SCHEMBL28212958 | 0.75 | LMNA (0.52) | MMP8ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002364-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2001-01-11 | — | — | WO | disclosed |