Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 7/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070722 | 0.90 | OPRL1 (0.40) | OPRL1KMT2ACCR1POLB | |
| SCHEMBL11078182 | 0.89 | SLC6A3 (0.32) | OPRL1 | |
| SCHEMBL11073068 | 0.89 | OPRL1 (0.35) | OPRL1KMT2APOLB | |
| SCHEMBL11069088 | 0.88 | — | — | |
| SCHEMBL11069208 | 0.85 | OPRL1 (0.38) | OPRL1KMT2ACCR1POLB | |
| SCHEMBL11074296 | 0.84 | OPRL1 (0.42) | OPRL1KMT2ACCR1POLB | |
| SCHEMBL11079016 | 0.80 | — | — | |
| SCHEMBL11077581 | 0.79 | OPRL1 (0.35) | OPRL1KMT2ACCR1POLB | |
| SCHEMBL11078645 | 0.78 | SLC6A3 (0.36) | OPRL1KMT2ACCR1 | |
| SCHEMBL11069810 | 0.78 | SLC6A4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |