Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064886 | 0.93 | ACE (0.62) | ACENAALAD2ECE1LMNAMME | |
| SCHEMBL11065217 | 0.90 | ACE (0.60) | ACENAALAD2ECE1LMNA | |
| SCHEMBL11067560 | 0.90 | ACE (0.60) | ACEALDH1A1NAALAD2ECE1LMNA | |
| SCHEMBL11063947 | 0.88 | ACE (0.60) | ACEALDH1A1NAALAD2ECE1LMNA | |
| SCHEMBL11068248 | 0.87 | FPR2 (0.61) | ACEALDH1A1 | |
| SCHEMBL11351754 | 0.86 | ACE (0.55) | ACENAALAD2MME | |
| SCHEMBL17624790 | 0.86 | NAALAD2 (0.68) | ACENAALAD2LMNAMMENPSR1 | |
| SCHEMBL17261298 | 0.86 | NAALAD2 (0.68) | ACENAALAD2LMNAMMENPSR1 | |
| SCHEMBL11274788 | 0.85 | ACE (0.53) | ACEALDH1A1NAALAD2MMENPSR1 | |
| SCHEMBL2806565 | 0.84 | FAAH (0.67) | ACENAALAD2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435329-A | ANTIHYPERTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-06 | — | — | US | disclosed |