SCHEMBL248246

SCHEMBL248246

O=C(O)CCCC(C(=O)O)c1cccccc2ccccccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.44
CYSLTR2 Q9NS75 1/20 0.43
CYSLTR1 Q9Y271 1/20 0.43
MAPK1 P28482 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP2D6 P10635 2/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
GLA P06280 1/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
NFKB1 P19838 1/20 0.42
APEX1 P27695 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MMP2 P08253 2/20 0.41
MMP9 P14780 2/20 0.41
MMP12 P39900 2/20 0.41
PTGER4 P35408 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8970371 0.94 PTGIR (0.45) KMT2ACYSLTR2CYSLTR1MAPK1ALDH1A1
SCHEMBL250429 0.90 MMP9 (0.49) KMT2AMAPK1ALDH1A1CYP2D6KDM4E
SCHEMBL5694338 0.87 KMT2A (0.46) KMT2AALDH1A1HPGDHSD17B10MMP2
SCHEMBL11069820 0.84 SOAT1 (0.44) KMT2ACYSLTR2CYSLTR1MAPK1ALDH1A1
SCHEMBL29418186 0.83 SOAT1 (0.47) KMT2ACYSLTR2CYSLTR1ALDH1A1KDM4E
SCHEMBL20564111 0.81 CYSLTR2 (0.46) CYSLTR2CYSLTR1MAPK1ALDH1A1CYP2D6
SCHEMBL11261260 0.80 KDM4E (0.50) KMT2AALDH1A1KDM4ESMN1; SMN2RXFP1
SCHEMBL8366593 0.80 KMT2A (0.46) KMT2AALDH1A1KDM4EHPGDMMP2
SCHEMBL20564404 0.79 CYSLTR2 (0.55) CYSLTR2CYSLTR1MAPK1ALDH1A1CYP2D6
Hydrochloric Acid SCHEMBL11247833 0.79 KDM4E (0.49) KMT2AALDH1A1KDM4ESMN1; SMN2RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9971265-B1 Toner compositions and processes XEROX CORPORATION (US) 2018-05-15 US claimed
US-9740124-B2 Toner compositions and processes XEROX CORPORATION (US) 2017-08-22 US claimed
US-20160349641-A1 TONER COMPOSITIONS AND PROCESSES XEROX CORPORATION (US) 2016-12-01 US claimed
US-9188895-B2 Toner additives for improved charging XEROX CORPORATION (US) 2015-11-17 US claimed
US-9128396-B2 Chemical binding of renewable oils to polyester emulsion XEROX CORPORATION (US) 2015-09-08 US claimed
US-20150168861-A1 TONER ADDITIVES FOR IMPROVED CHARGING XEROX CORPORATION (US) 2015-06-18 US claimed
US-20140178811-A1 CHEMICAL BINDING OF RENEWABLE OILS TO POLYESTER EMULSION XEROX CORPORATION (US) 2014-06-26 US claimed
US-8703379-B2 Chemical binding of renewable oils to polyester emulsion XEROX CORPORATION (US) 2014-04-22 US claimed
EP-2267547-B1 Toner comprising purified polyester resins and production method thereof XEROX CORP (US) 2014-02-26 EP claimed
US-20140030646-A1 CHEMICAL BINDING OF RENEWABLE OILS TO POLYESTER EMULSION XEROX CORPORATION (US) 2014-01-30 US claimed
US-20080197283-A1 EMULSION AGGREGATION TONER COMPOSITIONS AND DEVELOPERS XEROX CORPORATION (US) 2008-08-21 US claimed
US-20080113291-A1 EMULSION AGGREGATION TONER, DEVELOPER, AND METHOD OF MAKING THE SAME XEROX CORPORATION (US) 2008-05-15 US claimed
US-20080090163-A1 Emulsion aggregation processes XEROX CORPORATION (US) 2008-04-17 US claimed
US-20080063965-A1 Emulsion/aggregation processes using coalescent aid agents XEROX CORPORATION (US) 2008-03-13 US claimed
US-20070254228-A1 TONER COMPOSITIONS AND PROCESSES XEROX CORPORATION (US) 2007-11-01 US claimed
EP-1850187-A1 Toner Compostions and Processes Xerox Corporation (US) 2007-10-31 EP claimed
US-20070141495-A1 Emulsion/aggregation toners having novel dye complexes XEROX CORPORATION (US) 2007-06-21 US claimed
US-20070020542-A1 Emulsion aggregation, developer, and method of making the same XEROX CORPORATION (US) 2007-01-25 US claimed
US-20060105263-A1 Toner composition XEROX CORPORATION 2006-05-18 US claimed
US-5391452-A Polyester toner and developer compositions XEROX CORPORATION (US) 1995-02-21 US claimed