Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069820 | 0.87 | SOAT1 (0.44) | KMT2APPARAPPARGMAPTKCNQ2 | |
| SCHEMBL248246 | 0.87 | KMT2A (0.44) | KMT2APPARGMAPTTSHRCYP1A2 | |
| SCHEMBL29418186 | 0.85 | SOAT1 (0.47) | KMT2APPARAPPARGMAPTKCNQ2 | |
| SCHEMBL8970371 | 0.84 | PTGIR (0.45) | KMT2AMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL11261260 | 0.83 | KDM4E (0.50) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL250429 | 0.83 | MMP9 (0.49) | KMT2ATSHRCYP1A2HPGDLMNA | |
| SCHEMBL8366593 | 0.83 | KMT2A (0.46) | KMT2APPARAPPARGBCAT2MAPT | |
| Hydrochloric Acid SCHEMBL11247833 | 0.82 | KDM4E (0.49) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL11242992 | 0.79 | DRD3 (0.45) | KMT2AMAPTKCNQ2DRD3 | |
| SCHEMBL11122120 | 0.79 | CYP2C19 (0.46) | KMT2APPARAPPARGBCAT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654213-A1 | MATRIX METALLOPROTEINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-05-10 | — | — | EP | disclosed |
| WO-2004110974-A1 | MATRIX METALLOPROTEINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |