Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR1E | P28566 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493089 | 0.84 | LSS (0.31) | KDM4EALDH1A1TDP1 | |
| SCHEMBL526565 | 0.84 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL529337 | 0.84 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL6527091 | 0.83 | OPRK1 (0.35) | OPRK1OPRM1OPRD1KDM4EMEN1 | |
| SCHEMBL2699253 | 0.81 | ALDH1A1 (0.35) | OPRK1OPRM1OPRD1KDM4EMEN1 | |
| SCHEMBL1070246 | 0.79 | KCNH2 (0.31) | — | |
| SCHEMBL213436 | 0.75 | ALDH1A1 (0.35) | OPRK1OPRM1OPRD1KDM4EMEN1 | |
| SCHEMBL3519321 | 0.75 | TDP1 (0.32) | KDM4EADRA2ASLC6A2SLC6A4ADRA1A | |
| SCHEMBL11500604 | 0.74 | — | — | |
| SCHEMBL3655351 | 0.73 | KDM4E (0.33) | OPRK1OPRM1OPRD1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482743-A | (((DIALKYLAMINO)ALKYL)AMINO)ALKANONITRILE, BIS (( DIALKYLAMINO)ALKL)AMINE, ALKYLENE OXIDE | TEXACO INC. (US) | 1984-11-13 | — | — | US | claimed |