SCHEMBL526565

SCHEMBL526565

C=CCN(CC=C)CC=CO

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529337 1.00 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11500604 0.89
SCHEMBL11069859 0.84 OPRK1 (0.33) ALDH1A1
SCHEMBL10256711 0.82 TSHR (0.35) ALDH1A1
Hydrochloric Acid SCHEMBL29133447 0.82
SCHEMBL7549527 0.78 TSHR (0.43) ALDH1A1
SCHEMBL20656 0.78 TSHR (0.43) ALDH1A1
Formic Acid SCHEMBL7604832 0.77 ALDH1A1 (0.39) ALDH1A1
SCHEMBL6919007 0.76
SCHEMBL7464488 0.75 TSHR (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155153-B1 DYEING COMPOSITION COMPRISING A SPECIFIC AMINOPYRAZOLOPYRIDINE OXIDATION BASE, A COUPLER AND A SPECIFIC SURFACTANT L'ORÉAL (FR) 2017-03-01 EP claimed
EP-2651935-B1 DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER ORÉAL L (FR) 2016-11-23 EP claimed
US-9370477-B2 Dyeing composition comprising a fatty substance, a pyrazolopyridine oxidation base and a coupler L'OREAL (FR) 2016-06-21 US claimed
US-9175126-B2 Hydrophilic polyisocyanates EVONIK DEGUSSA GMBH (DE) 2015-11-03 US claimed
US-20130312203-A1 DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER L'OREAL (FR) 2013-11-28 US claimed
EP-2651935-A1 DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER L'Oréal (FR) 2013-10-23 EP claimed
EP-1992331-B1 Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol OREAL (FR) 2013-10-02 EP claimed
EP-2571913-A1 HYDROPHILIC POLYISOCYANATES Evonik Degussa GmbH (DE) 2013-03-27 EP claimed
US-20130041102-A1 HYDROPHILIC POLYISOCYANATES EVONIK DEGUSSA GMBH (DE) 2013-02-14 US claimed
WO-2012080324-A1 DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER L'OREAL (FR) 2012-06-21 WO claimed
WO-2011144644-A1 HYDROPHILIC POLYISOCYANATES EVONIK DEGUSSA GMBH (DE) 2011-11-24 WO claimed
US-7648536-B2 Method of coloring keratinous fibers comprising application of at least one aminopyrazolopyridine oxidation base in the absence of chemical oxidizing agents L'OREAL S.A. (FR) 2010-01-19 US claimed
US-7578856-B2 Dyeing compositions comprising at least one aminopyrazolopyridine oxidation base, at least one coupler and at least one C4-C30 polyol and methods and use thereof L'OREAL S.A. (FR) 2009-08-25 US claimed
US-20080289122-A1 Dyeing compositions comprising at least one aminopyrazolopyridine oxidation base, at least one coupler and at least one C4-C30 polyol and methods and use thereof L'OREAL S.A. (FR) 2008-11-27 US claimed
US-20080289121-A1 Method of coloring keratinous fibers comprising application of at least one aminopyrazolopyridine oxidation base in the absence of chemical oxidizing agents L'ORE'AL S.A. (FR) 2008-11-27 US claimed
EP-1992331-A1 Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol L'Oreal (FR) 2008-11-19 EP claimed
EP-1992330-A2 Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent L'Oreal (FR) 2008-11-19 EP claimed
EP-1992329-A1 Dyeing composition comprising an aminopyrazolopyridine oxidation base and a specific associative polymer L'Oréal (FR) 2008-11-19 EP claimed
EP-3694944-B1 PROTECTIVE FILMS MADE OF POLYOLEFIN SUPPORT MATERIAL, PRIMER AND RADIATION-CROSSLINKABLE HOT MELT ADHESIVE BASF SE (DE) 2024-04-24 EP disclosed
EP-0400435-A2 Carbonic half-ester of betaine structure BASF Aktiengesellschaft (DE) 1990-12-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130312203-A1 DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER ALDH5A1, SDHA, QDPR ALDH1A1 65/4885
US-20080289121-A1 Method of coloring keratinous fibers comprising application of at least one aminopyrazolopyridine oxidation base in the absence of chemical oxidizing agents KRT18, CYBB, NOX5 ALDH1A1 202/4885
US-20080289122-A1 Dyeing compositions comprising at least one aminopyrazolopyridine oxidation base, at least one coupler and at least one C4-C30 polyol and methods and use thereof CBR3, KRT18, PYCR1 ALDH1A1 331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.