Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1294703 | 0.84 | ADRA2A (0.56) | SMN1; SMN2USP2ALDH1A1CYP3A4GRM5 | |
| SCHEMBL1295044 | 0.83 | ALDH1A1 (0.64) | GAASMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL2129313 | 0.82 | ESR2 (0.53) | GRM5DRD2DRD1DRD5DRD3 | |
| SCHEMBL15863998 | 0.79 | ALDH1A1 (0.48) | GAASMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL20573444 | 0.78 | S1PR5 (0.52) | DRD2DRD1DRD5DRD3 | |
| SCHEMBL11067684 | 0.77 | ADRA2A (0.67) | SMN1; SMN2ALDH1A1CYP1A2CYP3A4GRM5 | |
| SCHEMBL12296389 | 0.77 | BCL2L1 (0.46) | SMN1; SMN2ALDH1A1MAPTKDM4EDRD2 | |
| SCHEMBL16268868 | 0.76 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1CYP3A4MAPTKDM4E | |
| SCHEMBL15864131 | 0.76 | L3MBTL1 (0.43) | GAASMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27310275 | 0.76 | TMEM97 (0.49) | SMN1; SMN2USP2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469634-A | Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines | SMITHKLINE BECKMAN CORPORATION (US) | 1984-09-04 | — | — | US | disclosed |
| EP-0103961-A1 | Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines | SMITHKLINE BECKMAN CORPORATION (US) | 1984-03-28 | — | — | EP | disclosed |