Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10510161 | 0.80 | HTR1A (0.44) | HTR6HTR1AKDM4ELMNADRD2 | |
| Hydrochloric Acid SCHEMBL10674226 | 0.80 | HTR1A (0.44) | HTR6HTR1AKDM4ELMNADRD2 | |
| SCHEMBL3772285 | 0.76 | CCNT1 (0.44) | HTR1AKDM4ELMNAALOX15DRD2 | |
| SCHEMBL3766147 | 0.74 | PPARG (0.52) | HTR6HTR1ADRD2SIGMAR1 | |
| SCHEMBL10510289 | 0.73 | DRD2 (0.45) | HTR6HTR1ADRD2HTR7DRD4 | |
| SCHEMBL10671532 | 0.72 | HTR1A (0.59) | HTR6HTR1AKDM4ELMNAALOX15 | |
| SCHEMBL29363627 | 0.70 | SIGMAR1 (0.60) | HTR1ADRD2DRD4SIGMAR1 | |
| SCHEMBL2781318 | 0.70 | PPARG (0.44) | HTR6HTR1AKDM4ELMNAALOX15 | |
| SCHEMBL2782763 | 0.70 | HTR1A (0.40) | HTR6HTR1AKDM4ELMNAALOX15 | |
| SCHEMBL30796599 | 0.70 | PDK4 (0.61) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435408-A | Dopaminergic stimulating and antianoxic 4-substituted 2H-indole-2-ones | ROUSSEL UCLAF (FR) | 1984-03-06 | — | — | US | disclosed |