Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 6/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | DRD2 | P14416 | 9/20 | 0.46 |
| ▸ | DRD3 | P35462 | 8/20 | 0.46 |
| ▸ | DRD4 | P21917 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066202 | 0.87 | SCN1A (0.54) | KCNH2DRD2DRD3DRD4 | |
| SCHEMBL11073822 | 0.87 | KCNH2 (0.54) | KCNH2MAOAMAOBDRD2 | |
| SCHEMBL11062991 | 0.85 | DRD2 (0.64) | MAOAMAOBDRD2DRD3DRD4 | |
| SCHEMBL11066799 | 0.85 | KCNH2 (0.65) | KCNH2MAOAMAOBDRD2DRD3 | |
| SCHEMBL11066876 | 0.84 | KCNH2 (0.51) | KCNH2MAOAMAOBDRD2 | |
| SCHEMBL11068217 | 0.83 | KCNH2 (0.57) | KCNH2MAOAMAOBDRD2DRD3 | |
| SCHEMBL11073528 | 0.82 | DRD2 (0.53) | KCNH2MAOAMAOBDRD2 | |
| SCHEMBL11063092 | 0.80 | DRD2 (0.53) | KCNH2MAOAMAOBDRD2 | |
| SCHEMBL10570672 | 0.79 | KCNH2 (0.72) | KCNH2DRD2DRD3DRD4 | |
| SCHEMBL11064138 | 0.79 | KCNH2 (0.64) | KCNH2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |