Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 7/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073822 | 0.90 | KCNH2 (0.54) | KCNH2DRD2PRMT5WDR77MAOA | |
| SCHEMBL11068217 | 0.90 | KCNH2 (0.57) | KCNH2DRD2PRMT5WDR77MAOA | |
| SCHEMBL11063092 | 0.85 | DRD2 (0.53) | KCNH2DRD2MAOAMAOBSCN1A | |
| SCHEMBL11073528 | 0.85 | DRD2 (0.53) | KCNH2DRD2MAOAMAOBSCN1A | |
| SCHEMBL11066799 | 0.85 | KCNH2 (0.65) | KCNH2DRD2MAOAMAOB | |
| SCHEMBL11070163 | 0.84 | KCNH2 (0.51) | KCNH2DRD2MAOAMAOB | |
| SCHEMBL11064138 | 0.83 | KCNH2 (0.64) | KCNH2PRMT5WDR77MAOAMAOB | |
| SCHEMBL11066202 | 0.82 | SCN1A (0.54) | KCNH2DRD2SCN1ASCN5ASCN9A | |
| SCHEMBL11071360 | 0.80 | MAOA (0.69) | KCNH2DRD2MAOAMAOBGAA | |
| SCHEMBL2053696 | 0.78 | KCNH2 (0.73) | KCNH2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |