SCHEMBL11070570

SCHEMBL11070570

Cc1cccc(Cl)c1N(C(=O)c1ccco1)C(C)Cl

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.51
RORC P51449 1/20 0.42
S1PR4 O95977 2/20 0.41
ATM Q13315 1/20 0.39
LCK P06239 2/20 0.38
POLB P06746 3/20 0.38
TSHR P16473 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4058016 0.79 OPRM1 (0.46) OPRM1S1PR4ATMPOLBKDM4E
SCHEMBL4058018 0.79 OPRM1 (0.46) OPRM1S1PR4ATMPOLBKDM4E
SCHEMBL11074068 0.76 OPRM1 (0.41) OPRM1RORCS1PR4LCK
Furalaxyl SCHEMBL22528 0.75 MEN1 (0.60) OPRM1RORCS1PR4ATMKDM4E
Furalaxyl SCHEMBL9661285 0.75 MEN1 (0.60) OPRM1RORCS1PR4ATMKDM4E
Furalaxyl SCHEMBL54624 0.75 MEN1 (0.60) OPRM1RORCS1PR4ATMKDM4E
SCHEMBL11833603 0.73 S1PR4 (0.49) OPRM1S1PR4ATMPOLBKDM4E
SCHEMBL11214373 0.71 LMNA (0.47) OPRM1S1PR4ATMPOLB
SCHEMBL11834127 0.71 S1PR4 (0.53) OPRM1S1PR4ATMPOLBTSHR
SCHEMBL10966168 0.69 S1PR4 (0.45) OPRM1S1PR4ATMPOLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4478848-A Combating fungi with substituted anilinomethylene-oximes BAYER AKTIENGESELLSCHAFT (DE) 1984-10-23 US disclosed
EP-0072970-A1 Substituted anilinomethylene oximes, method for their preparation and their use as herbicides BAYER AG (DE) 1983-03-02 EP disclosed