Furalaxyl

Furalaxyl

SCHEMBL54624

COC(=O)[C@H](C)N(C(=O)c1ccco1)c1c(C)cccc1C

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
PLA2G1B P04054 2/20 0.60
ATG4B Q9Y4P1 2/20 0.60
HTT P42858 2/20 0.60
NPSR1 Q6W5P4 1/20 0.60
S1PR4 O95977 1/20 0.50
ATM Q13315 1/20 0.43
OPRM1 P35372 3/20 0.41
RORC P51449 1/20 0.41
KDM4E B2RXH2 2/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
TP53 P04637 3/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
MAPK1 P28482 2/20 0.40
USP2 O75604 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Furalaxyl SCHEMBL22528 1.00 MEN1 (0.60) MEN1KMT2APLA2G1BATG4BHTT
Furalaxyl SCHEMBL9661285 1.00 MEN1 (0.60) MEN1KMT2APLA2G1BATG4BHTT
Benalaxyl SCHEMBL4297556 0.90 KMT2A (0.56) MEN1KMT2APLA2G1BATG4BHTT
Benalaxyl SCHEMBL727907 0.90 KMT2A (0.56) MEN1KMT2APLA2G1BATG4BHTT
Furalaxyl SCHEMBL5002959 0.87 MEN1 (0.47) MEN1KMT2APLA2G1BATG4BHTT
SCHEMBL11160412 0.86 KMT2A (0.48) MEN1KMT2APLA2G1BATG4BHTT
SCHEMBL4058018 0.85 OPRM1 (0.46) MEN1KMT2APLA2G1BATG4BHTT
SCHEMBL4058016 0.85 OPRM1 (0.46) MEN1KMT2APLA2G1BATG4BHTT
SCHEMBL11153293 0.83 KMT2A (0.45) MEN1KMT2APLA2G1BATG4BHTT
Furalaxyl SCHEMBL19384964 0.82 HTT (0.43) MEN1KMT2APLA2G1BATG4BHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030055096-A1 Fungicidal composition OGURI YUKIO (JP) 2003-03-20 US claimed
EP-0610764-B1 Fungicidal mixture BAYER AG (DE) 1999-05-12 EP claimed
JP-2582885-B2 1997-02-19 JP claimed
EP-0741970-A1 BACTERICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-13 EP claimed
EP-0193922-B1 FUNGICIDAL AND PLANT GROWTH REGULATING AGENTS CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1992-03-11 EP claimed
EP-0305442-A1 FUNGICIDE COMPOSITIONS. CHINOIN GYOGYSZER ES VEGYESZET (HU) 1989-03-08 EP claimed
WO-1988006841-A1 FUNGICIDE COMPOSITIONS Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) 1988-09-22 WO claimed
US-8877681-B2 Use of specific alcohol alkoxylates as an adjuvant for agrotechnical applications BASF SE (DE) 2014-11-04 US disclosed
US-8802120-B2 Bioactive agrichemical compositions and use thereof SCIESSENT LLC (US) 2014-08-12 US disclosed
EP-1659864-B1 METHOD OF PLANT GROWTH PROMOTION USING AMIDE COMPOUNDS BASF SE (DE) 2013-09-18 EP disclosed
US-20130012556-A1 Bioactive Agrichemical Compositions and Use Thereof SCIESSENT LLC (US) 2013-01-10 US disclosed
US-20120264607-A1 USE OF SPECIFIC ALCOHOL ALKOXYLATES AS AN ADJUVANT FOR AGROTECHNICAL APPLICATIONS BERGHAUS RAINER (DE) 2012-10-18 US disclosed
US-8287893-B2 Bioactive agrichemical compositions and use thereof SCIESSENT LLC (US) 2012-10-16 US disclosed
US-4514402-A 1,2,4-TRIAZOLE AND QUINOXALINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1985-04-30 US disclosed
EP-0088256-A1 Fungicidal agent BAYER AG (DE) 1983-09-14 EP disclosed
US-4272551-A N-Sulfenylated formanilides useful as fungicides and bactericides BASF AKTIENGESELLSCHAFT (DE) 1981-06-09 US disclosed
EP-0008731-B1 N-SULFENYL FORMANILIDES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES BASF Aktiengesellschaft (DE) 1981-05-13 EP disclosed
US-4261924-A FUNGICIDES, BACTERICIDES BASF AKTIENGESELLSCHAFT (DE) 1981-04-14 US disclosed
EP-0008731-A1 N-sulfenyl formanilides, their preparation and their use as fungicides BASF Aktiengesellschaft (DE) 1980-03-19 EP disclosed
EP-0002671-A1 Triazolylglycol ethers, process for their preparation and their use as fungicides BASF Aktiengesellschaft (DE) 1979-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120264607-A1 USE OF SPECIFIC ALCOHOL ALKOXYLATES AS AN ADJUVANT FOR AGROTECHNICAL APPLICATIONS ADH5, ALKBH3, ADH1C MEN1 4485/4885KMT2A 2925/4885PLA2G1B 246/4885
US-20030055096-A1 Fungicidal composition CBR1, CBR3, CYP1B1 MEN1 1994/4885KMT2A 2342/4885PLA2G1B 4233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.