Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488677 | 0.92 | FAAH (0.38) | MLYCDALDH1A1MAPTFAAH | |
| SCHEMBL11488679 | 0.92 | FAAH (0.38) | MLYCDALDH1A1MAPTFAAH | |
| SCHEMBL11174731 | 0.85 | NAAA (0.34) | MLYCDKMT2A | |
| SCHEMBL3270531 | 0.78 | NPC1 (0.45) | MLYCDNPC1RAB9AJAK2PAX8 | |
| SCHEMBL11070556 | 0.78 | NPC1 (0.48) | MLYCDNPC1RAB9AJAK2PAX8 | |
| SCHEMBL11559695 | 0.77 | NPC1 (0.47) | MLYCDNPC1RAB9AJAK2PAX8 | |
| SCHEMBL11562137 | 0.77 | NPC1 (0.47) | MLYCDNPC1RAB9AJAK2PAX8 | |
| SCHEMBL11063213 | 0.77 | NPC1 (0.47) | MLYCDNPC1RAB9AJAK2PAX8 | |
| SCHEMBL11555883 | 0.77 | NPC1 (0.47) | MLYCDNPC1RAB9AJAK2PAX8 | |
| SCHEMBL11561291 | 0.77 | NPC1 (0.47) | MLYCDNPC1RAB9AJAK2PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485105-A | Method of treating hyperlipidemia with 4-(monoalkylamino)benzoic acid amides | AMERICAN CYANAMID COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| US-4242273-A | ANTILIPEMIC AND ANTICHOLESTEROL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4136256-A | HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |