Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490974 | 0.89 | ALDH1A1 (0.40) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL11067692 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TDP1MAPTHPGDCCR6 | |
| SCHEMBL11492891 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDPAX8PPARA | |
| SCHEMBL3938149 | 0.74 | ALDH1A1 (0.37) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL3935516 | 0.72 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDCCR6PAX8 | |
| SCHEMBL2615683 | 0.72 | ALDH1A1 (0.47) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL11178153 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL11067881 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL11070772 | 0.70 | PAX8 (0.50) | ALDH1A1TDP1MAPTHPGDCCR6 | |
| SCHEMBL15001656 | 0.69 | CCR6 (0.56) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |