Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490974 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TGM2CCR6PAX8LMNA | |
| SCHEMBL11070809 | 0.81 | PTPN1 (0.35) | ALDH1A1TGM2CCR6PAX8HCAR2 | |
| SCHEMBL11492891 | 0.73 | ALDH1A1 (0.43) | ALDH1A1PAX8MAPTHPGD | |
| SCHEMBL4651960 | 0.72 | ALDH1A1 (0.49) | ALDH1A1CCR6PAX8LMNAHCAR2 | |
| SCHEMBL15001656 | 0.71 | CCR6 (0.56) | ALDH1A1TGM2CCR6PAX8LMNA | |
| SCHEMBL27353515 | 0.71 | TGM2 (0.51) | ALDH1A1TGM2CCR6PAX8LMNA | |
| SCHEMBL504963 | 0.70 | CCR6 (0.52) | ALDH1A1TGM2CCR6PAX8LMNA | |
| SCHEMBL10240182 | 0.68 | CCR6 (0.55) | ALDH1A1TGM2CCR6PAX8LMNA | |
| SCHEMBL11070648 | 0.68 | FAAH (0.41) | ALDH1A1PAX8TRPV1KDM4EMAPT | |
| SCHEMBL11070645 | 0.68 | FAAH (0.41) | ALDH1A1PAX8TRPV1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |