Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.79 |
| ▸ | PPARA | Q07869 | 8/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063131 | 0.94 | OPRK1 (0.81) | OPRK1PPARACYP1A2CYP3A4ABCB11 | |
| Beclobrate SCHEMBL49779 | 0.88 | OPRK1 (1.00) | OPRK1PPARACYP1A2CYP3A4ABCB11 | |
| Beclobrate SCHEMBL3950803 | 0.88 | OPRK1 (1.00) | OPRK1PPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL11074943 | 0.83 | PPARA (0.86) | OPRK1PPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL11066953 | 0.82 | OPRK1 (0.63) | OPRK1PPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL1935420 | 0.81 | OPRK1 (0.86) | OPRK1PPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL11071767 | 0.81 | OPRK1 (0.81) | OPRK1PPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL11412149 | 0.80 | PPARA (0.51) | OPRK1PPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL11639698 | 0.79 | OPRK1 (0.62) | OPRK1PPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL7406839 | 0.79 | OPRK1 (0.69) | OPRK1PPARACYP1A2CYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483999-A | Phenoxy alkanoic acid derivatives having the ability to lower the level of fatty substances in the blood | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1984-11-20 | — | — | US | disclosed |