SCHEMBL11070922

SCHEMBL11070922

CC(C)(C)N1C(=O)CN(c2ccccc2)C1=S

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
MAPT P10636 3/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 4/20 0.44
CTSG P08311 5/20 0.40
CMA1 P23946 4/20 0.40
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 2/20 0.38
LOX P28300 1/20 0.38
USP2 O75604 1/20 0.38
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11088145 0.82 CTSG (0.49) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL11066753 0.77 NPC1 (0.54) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL11930033 0.77 NPC1 (0.44) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL1685398 0.74 KMT2A (0.56) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL6401098 0.73 NPC1 (0.54) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL11064251 0.72 KMT2A (0.50) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL10383197 0.72 NPC1 (0.50) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL11072116 0.70 KMT2A (0.49) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL11074111 0.70 KMT2A (0.48) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL9834330 0.70 KMT2A (0.61) KMT2ANPC1RAB9AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4473393-A INSECTICIDES, MITICIDES, NEMATOCIDES, FUNGICIDES, AND HERBICIDE BUFFALO COLOR CORPORATION (US) 1984-09-25 US disclosed