Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072116 | 0.90 | KMT2A (0.49) | KMT2ANPC1RAB9AKDM4EGAA | |
| SCHEMBL11065342 | 0.90 | HTT (0.53) | KMT2ANPC1RAB9AKDM4EGAA | |
| SCHEMBL5955129 | 0.87 | PLCG1 (0.55) | KMT2ANPC1RAB9AKDM4EGAA | |
| SCHEMBL11638136 | 0.87 | NPC1 (0.56) | KMT2ANPC1RAB9AGAAMEN1 | |
| SCHEMBL5955047 | 0.87 | KMT2A (0.56) | KMT2ANPC1RAB9AKDM4EGAA | |
| SCHEMBL5955275 | 0.87 | KMT2A (0.56) | KMT2ANPC1RAB9AKDM4EGAA | |
| SCHEMBL11071726 | 0.86 | CTSG (0.51) | KMT2ANPC1RAB9AKDM4EGAA | |
| SCHEMBL6626141 | 0.84 | MAPT (0.53) | KMT2ANPC1RAB9AKDM4EGAA | |
| SCHEMBL11147745 | 0.84 | DUSP22 (0.47) | KMT2ANPC1RAB9AKDM4EGAA | |
| SCHEMBL23365830 | 0.83 | DDB1 (0.47) | KMT2ANPC1RAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551182-A1 | TOPICAL PHARMACEUTICAL COMPOSITION CONTAINING PHENYTOIN AND A (CO -)AN ALGESIC FOR THE TREATMENT OF CHRONIC PAIN | TOPICAL INNOVATIONS B.V. (NL) | 2019-10-16 | — | — | EP | claimed |
| WO-2018106108-A1 | TOPICAL PHARMACEUTICAL COMPOSITION CONTAINING PHENYTOIN AND A (CO -)AN ALGESIC FOR THE TREATMENT OF CHRONIC PAIN | KEPPEL HESSELING, Jan Marius (NL) | 2018-06-14 | — | — | WO | claimed |
| US-20130005786-A1 | THERAPEUTIC INVENTION | KAPOOR RAJU (GB) | 2013-01-03 | — | — | US | claimed |
| EP-3551182-B1 | TOPICAL PHARMACEUTICAL COMPOSITION CONTAINING PHENYTOIN AND A (CO -)AN ALGESIC FOR THE TREATMENT OF CHRONIC PAIN | TOPICAL INNOVATIONS B V (NL) | 2025-03-19 | — | — | EP | disclosed |
| EP-3551166-B1 | TOPICAL PHENYTOIN FOR USE IN THE TREATMENT OF PERIPHERAL NEUROPATHIC PAIN | TOPICAL INNOVATIONS B V (NL) | 2024-08-21 | — | — | EP | disclosed |
| US-11285099-B2 | Topical phenytoin for use in the treatment of peripheral neuropathic pain | TOPICAL INNOVATIONS B.V. (NL) | 2022-03-29 | — | — | US | disclosed |
| US-11147799-B2 | Topical pharmaceutical composition containing phenytoin and a (co-) analgesic for the treatment of chronic pain | Keppel Hesselink, Jan Marius (NL) | 2021-10-19 | — | — | US | disclosed |
| US-20200276106-A1 | TOPICAL PHENYTOIN FOR USE IN THE TREATMENT OF PERIPHERAL NEUROPATHIC PAIN | TOPICAL INNOVATIONS B.V. (NL) | 2020-09-03 | — | — | US | disclosed |
| US-20200069649-A1 | TOPICAL PHARMACEUTICAL COMPOSITION CONTAINING PHENYTOIN AND A (CO -) ANALGESIC FOR THE TREATMENT OF CHRONIC PAIN | TOPICAL INNOVATIONS B.V. (NL) | 2020-03-05 | — | — | US | disclosed |
| EP-3551166-A1 | TOPICAL PHENYTOIN FOR USE IN THE TREATMENT OF PERIPHERAL NEUROPATHIC PAIN | TOPICAL INNOVATIONS B.V. (NL) | 2019-10-16 | — | — | EP | disclosed |
| EP-3551182-A1 | TOPICAL PHARMACEUTICAL COMPOSITION CONTAINING PHENYTOIN AND A (CO -)AN ALGESIC FOR THE TREATMENT OF CHRONIC PAIN | TOPICAL INNOVATIONS B.V. (NL) | 2019-10-16 | — | — | EP | disclosed |
| US-RE29168-E | HEAT SENSITIVE, ANTIHALATION LAYER | EASTMAN KODAK COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4007170-A | SILVER HALIDE SENSITIZERS | EASTMAN KODAK COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
| US-4002480-A | CONTAINING A DINUCLEAR MEROCYANINE SENSITIZING DYE AND AN ANTIFOGGING AGENT | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-11 | — | — | US | disclosed |
| US-3976661-A | SENSITIZERS, FILTERS | EASTMAN KODAK COMPANY (US) | 1976-08-24 | — | — | US | disclosed |
| US-3951666-A | CYANINE AND MEROCYANINE DYES | FUJI PHOTO FILM CO., LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
| US-3943142-A | Dye intermediates and their preparation and use in the synthesis of methine dyes | EASTMAN KODAK COMPANY (US) | 1976-03-09 | — | — | US | disclosed |
| US-3936308-A | Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
| US-3935010-A | IMIDAZOQUINOXALINE DESENSITIZER | EASTMAN KODAK COMPANY (US) | 1976-01-27 | — | — | US | disclosed |
| US-3932182-A | An organic photoconductive composition comprising an organic photoconductive compound and a sensitizing compound having an active methylene group | MITSUBISHI PAPER MILLS, LTD. (JA) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005786-A1 | THERAPEUTIC INVENTION | AQP4, PMP22, NHERF1 | KMT2A 2062/4885NPC1 409/4885RAB9A 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.