Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL11071045

Cc1cc([N+](=O)[O-])ccc1[N+]#N.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
TDP1 Q9NUW8 2/20 0.46
TSHR P16473 2/20 0.46
CYP3A4 P08684 3/20 0.44
PDE2A O00408 1/20 0.40
PDE5A O76074 1/20 0.40
ALOX15 P16050 1/20 0.40
NFKB1 P19838 1/20 0.40
APEX1 P27695 1/20 0.40
PDE4A P27815 1/20 0.40
BLM P54132 1/20 0.40
PDE1B Q01064 1/20 0.40
PMP22 Q01453 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4D Q08499 1/20 0.40
PDE7A Q13946 1/20 0.40
PDE1C Q14123 1/20 0.40
PDE7B Q9NP56 1/20 0.40
NHERF1 O14745 1/20 0.38
MCL1 Q07820 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6650089 0.87 ALDH1A1 (0.60) ALDH1A1TDP1TSHRCYP3A4PDE2A
SCHEMBL11430708 0.84 ALDH1A1 (0.53) ALDH1A1TDP1TSHRCYP3A4PDE2A
Trifluoromethanesulfonic Acid SCHEMBL9471147 0.83 GPR35 (0.44) ALDH1A1TDP1TSHRGRIA1GRIA2
Sulfuric Acid SCHEMBL8930779 0.78 ALDH1A1 (0.53) ALDH1A1TDP1TSHRCYP3A4PDE2A
Trifluoromethanesulfonic Acid SCHEMBL11070798 0.78 TSHR (0.46) TDP1TSHRCYP3A4LMNAKAT2B
Trifluoromethanesulfonic Acid SCHEMBL9471130 0.76 CA1 (0.46) ALDH1A1GRIA1GRIA2GRIA3GRIA4
SCHEMBL11658463 0.76 TSHR (0.47) ALDH1A1TDP1TSHRCYP3A4PDE2A
Sulfuric Acid SCHEMBL8930788 0.75 ALDH1A1 (0.50) ALDH1A1TDP1TSHRCYP3A4PDE2A
SCHEMBL11658461 0.74 ALDH1A1 (0.49) ALDH1A1TDP1TSHRCYP3A4PDE2A
Trifluoromethanesulfonic Acid SCHEMBL11061600 0.74 S100B (0.42) ALDH1A1CYP3A4ALOX15L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4482489-A USEFUL IN DIAZOTYPE SYSTEMS AND AS LATENT POLYMERIZATION INITIATORS JAMES RIVER GRAPHICS, INC. (US) 1984-11-13 US disclosed