Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 8/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11189829 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1ACEHSD17B10 | |
| SCHEMBL11186430 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11100929 | 0.88 | HSD17B10 (0.52) | ACEHSD17B10 | |
| SCHEMBL11200469 | 0.87 | POLB (0.48) | ACE | |
| SCHEMBL11244020 | 0.87 | POLB (0.48) | ACE | |
| SCHEMBL11234749 | 0.84 | ACE (0.47) | KDM4EALDH1A1ACEHSD17B10 | |
| SCHEMBL11071092 | 0.84 | ACE (0.44) | ACEHSD17B10 | |
| SCHEMBL9853999 | 0.82 | POLB (0.58) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11107571 | 0.81 | POLB (0.49) | ACE | |
| SCHEMBL11234757 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356183-A | ENZYME INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-10-26 | — | — | US | claimed |