Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.48 |
| ▸ | MAOA | P21397 | 14/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11065038 | 0.82 | MAOB (0.48) | MAOBMAOADRD2AOC3 | |
| Iodide SCHEMBL11063509 | 0.81 | ADRB1 (0.54) | — | |
| SCHEMBL11064783 | 0.79 | DRD2 (0.60) | MAOBMAOADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11073701 | 0.77 | DRD2 (0.49) | MAOBMAOADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11073533 | 0.75 | DRD2 (0.44) | MAOBMAOADRD2AOC3 | |
| SCHEMBL11725436 | 0.74 | MAOB (0.57) | MAOBMAOAAOC3 | |
| SCHEMBL2021136 | 0.73 | KCNH2 (0.64) | MAOBMAOADRD2DRD4DRD3 | |
| SCHEMBL2021138 | 0.73 | KCNH2 (0.64) | MAOBMAOADRD2DRD4DRD3 | |
| SCHEMBL2024412 | 0.73 | KCNH2 (0.64) | MAOBMAOADRD2DRD4DRD3 | |
| Iodide SCHEMBL11064437 | 0.73 | MAOB (0.53) | MAOBMAOADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |