Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071456 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL11297551 | 0.85 | MAPT (0.41) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL11297553 | 0.85 | MAPT (0.41) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL11155678 | 0.82 | KMT2A (0.56) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL11318573 | 0.79 | MAPT (0.37) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL11067487 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL11073671 | 0.75 | EGFR (0.54) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL9487727 | 0.74 | MAPT (0.50) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL10832665 | 0.74 | AKR1C3 (0.45) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL877659 | 0.73 | AKR1C3 (0.59) | SMN1; SMN2NPC1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |