Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301916 | 0.85 | AURKA (0.40) | SMN1; SMN2ALDH1A1RAB9AKMT2ANPC1 | |
| SCHEMBL11155678 | 0.81 | KMT2A (0.56) | SMN1; SMN2LMNANPSR1HPGDKDM4E | |
| SCHEMBL11166563 | 0.77 | KDM4E (0.51) | HPGDKDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL1436172 | 0.76 | SLC7A5 (0.49) | SMN1; SMN2NPSR1KDM4EALDH1A1RAB9A | |
| SCHEMBL11071275 | 0.76 | ALDH1A1 (0.43) | LMNANPSR1HPGDKDM4EALDH1A1 | |
| SCHEMBL11071458 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNANPSR1HPGDKDM4E | |
| SCHEMBL11071456 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNANPSR1HPGDKDM4E | |
| SCHEMBL31439643 | 0.75 | SLC7A5 (0.48) | SMN1; SMN2NPSR1KDM4EALDH1A1RAB9A | |
| SCHEMBL11073671 | 0.74 | EGFR (0.54) | SMN1; SMN2HPGDALDH1A1RAB9AKMT2A | |
| SCHEMBL2036336 | 0.74 | NPC1 (0.54) | SMN1; SMN2LMNAALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |