Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297551 | 1.00 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1TP53LMNA | |
| SCHEMBL11071456 | 0.85 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL11071458 | 0.85 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL11318573 | 0.81 | MAPT (0.37) | MAPTSMN1; SMN2ALDH1A1TP53LMNA | |
| SCHEMBL11410033 | 0.80 | TSHR (0.57) | MAPTSMN1; SMN2ALDH1A1TP53KMT2A | |
| SCHEMBL11467331 | 0.80 | CA1 (0.56) | MAPTSMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL11159031 | 0.78 | PTGER4 (0.42) | MAPTSMN1; SMN2ALDH1A1TP53HTT | |
| SCHEMBL11497015 | 0.76 | TSHR (0.47) | MAPTSMN1; SMN2ALDH1A1TP53LMNA | |
| SCHEMBL9487727 | 0.75 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL11301916 | 0.73 | AURKA (0.40) | MAPTSMN1; SMN2ALDH1A1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281019-A | 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents | AMERICAN CYANAMID COMPANY (US) | 1981-07-28 | — | — | US | disclosed |