Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074828 | 0.80 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL8142294 | 0.76 | ADAM17 (0.31) | — | |
| SCHEMBL8143113 | 0.73 | AR (0.31) | DGAT1 | |
| SCHEMBL1629800 | 0.72 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL65055 | 0.70 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL2184251 | 0.70 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL2185566 | 0.70 | DGAT1 (0.41) | DGAT1 | |
| Ammonia Solution, Strong SCHEMBL28085860 | 0.70 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL6049430 | 0.69 | KCNN4 (0.42) | — | |
| SCHEMBL12494033 | 0.69 | DGAT1 (0.39) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448980-A | BY CARBONYLATION WITH BIFLUORIDE CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-15 | — | — | US | disclosed |