Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.43 |
| ▸ | PDE9A | O76083 | 7/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729400 | 0.70 | KDM4E (0.46) | ALDH1A1HPGDNPC1LMNARAB9A | |
| SCHEMBL11068693 | 0.69 | LRRK2 (0.38) | KDM4DALDH1A1HPGDLMNALIMK1 | |
| SCHEMBL11071942 | 0.66 | ALDH1A1 (0.43) | ALDH1A1HPGDNPC1LMNAMAPT | |
| SCHEMBL7348659 | 0.65 | PDE9A (0.39) | KDM4DPDE9AKCNMA1ALDH1A1HPGD | |
| SCHEMBL16283937 | 0.64 | HPGD (0.43) | ALDH1A1HPGDNPC1LMNAMAPT | |
| SCHEMBL15827544 | 0.63 | HPGD (0.42) | ALDH1A1HPGDNPC1LMNAMAPT | |
| SCHEMBL11071485 | 0.63 | LRRK2 (0.39) | KDM4DALDH1A1HPGDLMNALIMK1 | |
| SCHEMBL23099071 | 0.62 | LIMK1 (0.37) | KCNMA1ALDH1A1LIMK1 | |
| SCHEMBL271817 | 0.62 | LIMK1 (0.41) | ALDH1A1HPGDNPC1LMNAMAPT | |
| SCHEMBL10981876 | 0.62 | ALDH1A1 (0.39) | KDM4DPDE9AALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474786-A | CONGESTIVE HEART FAILURE | SCHERING CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0102046-A1 | Tricyclic lactams, method for making them, pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-03-07 | — | — | EP | disclosed |