Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | DRD1 | P21728 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11065365 | 0.96 | CYP2J2 (0.52) | CYP2J2ADRA1ACHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL11068630 | 0.90 | ADRA1D (0.54) | CYP2J2ADRA1ACHRM2HTR1AADRA2A | |
| SCHEMBL11073339 | 0.90 | DRD2 (0.60) | ADRA1ACHRM2HTR1AADRA2ADRD1 | |
| Hydrochloric Acid SCHEMBL11065041 | 0.89 | DRD2 (0.59) | ADRA1ACHRM2HTR1AADRA2ADRD1 | |
| SCHEMBL11360921 | 0.83 | KCNH2 (0.59) | CYP2J2ADRA1ACHRM2HTR1AADRA2A | |
| SCHEMBL11073410 | 0.81 | DRD4 (0.51) | CYP2J2ADRA1AHTR1ADRD2ADRA1D | |
| SCHEMBL11071560 | 0.80 | DRD2 (0.61) | CYP2J2ADRA1ACHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL11367354 | 0.79 | KCNH2 (0.57) | CYP2J2KCNH2SLC6A2SLC6A4DRD4 | |
| SCHEMBL11354457 | 0.78 | TMEM97 (0.55) | CYP2J2SLC6A2SLC6A4DRD4ACHE | |
| SCHEMBL12142398 | 0.77 | ADRA1A (0.79) | CYP2J2ADRA1ACHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |