Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.78 |
| ▸ | PPARA | Q07869 | 9/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | FABP2 | P12104 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19183361 | 0.93 | OPRK1 (0.66) | OPRK1PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL11071169 | 0.88 | OPRK1 (0.76) | OPRK1PPARAPPARGCYP1A2CYP3A4 | |
| Beclobrate SCHEMBL3950803 | 0.88 | OPRK1 (1.00) | OPRK1PPARAPPARGCYP1A2CYP3A4 | |
| Beclobrate SCHEMBL49779 | 0.88 | OPRK1 (1.00) | OPRK1PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL11478612 | 0.86 | OPRK1 (0.73) | OPRK1PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL11073216 | 0.86 | OPRK1 (0.73) | OPRK1PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL11071767 | 0.85 | OPRK1 (0.81) | OPRK1PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL11068359 | 0.85 | OPRK1 (0.73) | OPRK1PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL11470655 | 0.84 | OPRK1 (0.79) | OPRK1PPARAPPARGCYP1A2CYP3A4 | |
| SCHEMBL12853898 | 0.81 | OPRK1 (0.50) | OPRK1ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483999-A | Phenoxy alkanoic acid derivatives having the ability to lower the level of fatty substances in the blood | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1984-11-20 | — | — | US | disclosed |