Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948073 | 0.81 | MEN1 (0.60) | MEN1KMT2ATAS1R3TAS1R1KDM4E | |
| SCHEMBL28012455 | 0.80 | MEN1 (0.46) | MEN1KMT2ATHRATHRBTAS1R3 | |
| SCHEMBL6812174 | 0.79 | SMN1; SMN2 (0.73) | KDM4ESMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL6808384 | 0.79 | KMT2A (0.49) | MEN1KMT2ATHRATHRBTAS1R3 | |
| SCHEMBL8011974 | 0.78 | MAPT (0.55) | MEN1KMT2AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL28162947 | 0.77 | PDE4B (0.47) | MEN1KMT2ATHRATHRBTAS1R3 | |
| SCHEMBL15943001 | 0.77 | THRA (0.61) | THRATHRB | |
| SCHEMBL28012472 | 0.76 | MEN1 (0.44) | MEN1KMT2ATHRATHRBTAS1R3 | |
| SCHEMBL6808423 | 0.76 | SMN1; SMN2 (0.76) | MEN1KMT2ATHRBKDM4ESMN1; SMN2 | |
| SCHEMBL10799135 | 0.75 | KMT2A (0.51) | MEN1KMT2ATHRATHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450115-A | ADRENERGIC BLOCKING AGENTS; HYPOTENSIVE AND CARDIOTONIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1984-05-22 | — | — | US | disclosed |