Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080022 | 0.89 | NFKB1 (0.47) | ALOX15ALOX12NFKB1NFKB2RELA | |
| SCHEMBL11080308 | 0.81 | CA12 (0.44) | ALOX15ALOX12NFKB1NFKB2RELA | |
| SCHEMBL11076881 | 0.81 | CYP19A1 (0.49) | ALOX15ALOX12NFKB1NFKB2RELA | |
| SCHEMBL11083650 | 0.79 | NFKB1 (0.51) | NFKB1NFKB2RELACYP19A1CA2 | |
| SCHEMBL11080406 | 0.78 | CYP19A1 (0.46) | NFKB1NFKB2RELACYP19A1CA2 | |
| SCHEMBL11081634 | 0.73 | CYP3A4 (0.43) | ALOX15ALOX12NFKB1NFKB2RELA | |
| SCHEMBL11080733 | 0.72 | TUBB4A (0.42) | ALOX15ALOX12NFKB1NFKB2RELA | |
| SCHEMBL11086603 | 0.70 | NPC1 (0.42) | ALOX15ALOX12NFKB1NFKB2RELA | |
| SCHEMBL28286860 | 0.66 | KDM1A (0.44) | ALOX15ALOX12CYP19A1CA2KDM1A | |
| SCHEMBL11084825 | 0.66 | KDM1A (0.39) | NFKB1NFKB2RELACA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436749-A | CARDIOVASCULAR DISORDERS | PIERRE FABRE S.A. (FR) | 1984-03-13 | — | — | US | disclosed |