Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080022 | 0.88 | NFKB1 (0.47) | CYP19A1NFKB1NFKB2RELACA2 | |
| SCHEMBL11083650 | 0.85 | NFKB1 (0.51) | CYP19A1NFKB1NFKB2RELACA2 | |
| SCHEMBL11073047 | 0.78 | ALOX15 (0.39) | CYP19A1NFKB1NFKB2RELACA2 | |
| SCHEMBL11076881 | 0.77 | CYP19A1 (0.49) | CYP19A1NFKB1NFKB2RELAMAPT | |
| SCHEMBL11080308 | 0.77 | CA12 (0.44) | CYP19A1NFKB1NFKB2RELAMAPT | |
| SCHEMBL30317850 | 0.71 | LMNA (0.47) | CYP19A1MAPTHTR2CNPC1KDM4E | |
| SCHEMBL25264495 | 0.70 | NFKB1 (0.69) | CYP19A1NFKB1NFKB2RELACA2 | |
| SCHEMBL25187265 | 0.70 | NFKB1 (0.69) | CYP19A1NFKB1NFKB2RELACA2 | |
| SCHEMBL5498695 | 0.69 | CYP19A1 (0.83) | CYP19A1NFKB1NFKB2RELAMAPT | |
| SCHEMBL17227888 | 0.69 | NFKB1 (0.53) | CYP19A1NFKB1NFKB2RELAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436749-A | CARDIOVASCULAR DISORDERS | PIERRE FABRE S.A. (FR) | 1984-03-13 | — | — | US | disclosed |