Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302159 | 0.86 | HSD11B1 (0.57) | HSD11B1RECQLMEN1KMT2ANPC1 | |
| SCHEMBL10832665 | 0.78 | AKR1C3 (0.45) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL877659 | 0.78 | AKR1C3 (0.59) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL11075790 | 0.78 | NR4A2 (0.49) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL370664 | 0.77 | AKR1C3 (0.44) | NPC1ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL452973 | 0.74 | HSD11B1 (0.77) | HSD11B1RECQLMEN1KMT2ANPC1 | |
| Isophthalic Acid SCHEMBL27427891 | 0.74 | AKR1C3 (0.54) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL10972252 | 0.74 | CA1 (0.50) | ALDH1A1TSHRHSD17B10CA12CA2 | |
| SCHEMBL370685 | 0.74 | HCAR3 (0.44) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL29609513 | 0.73 | HSD11B1 (0.74) | HSD11B1RECQLMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |