SCHEMBL8000122

SCHEMBL8000122

CC1(O)CCc2ccccc2C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 9/20 0.54
HTR2A P28223 8/20 0.54
HTR2C P28335 8/20 0.54
HTR2B P41595 8/20 0.54
CES1 P23141 1/20 0.45
DRD2 P14416 7/20 0.43
MAPT P10636 3/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 2/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
MAPK1 P28482 1/20 0.42
CASP1 P29466 1/20 0.42
CA7 P43166 1/20 0.42
RECQL P46063 1/20 0.42
BACE1 P56817 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5902887 0.81 SIGMAR1 (0.53) SIGMAR1HTR2AHTR2CHTR2BCES1
SCHEMBL29447988 0.81 SIGMAR1 (0.57) SIGMAR1HTR2AHTR2CHTR2BCES1
SCHEMBL11073092 0.81 L3MBTL1 (0.47) SIGMAR1HTR2AHTR2CHTR2BMAPT
SCHEMBL3054003 0.81 SIGMAR1 (0.57) SIGMAR1HTR2AHTR2CHTR2BCES1
SCHEMBL14358027 0.79 SIGMAR1 (0.56) SIGMAR1HTR2AHTR2CHTR2BCES1
SCHEMBL27690460 0.78 SIGMAR1 (0.50) SIGMAR1HTR2AHTR2CHTR2BCES1
SCHEMBL6448738 0.78 SIGMAR1 (0.54) SIGMAR1HTR2AHTR2CHTR2BCES1
SCHEMBL12083295 0.77 SIGMAR1 (0.50) SIGMAR1HTR2AHTR2CHTR2BCES1
SCHEMBL30992145 0.77 HTR2A (0.50) SIGMAR1HTR2AHTR2CHTR2BCES1
SCHEMBL27522505 0.77 SIGMAR1 (0.50) SIGMAR1HTR2AHTR2CHTR2BCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3902878-B1 PHOTOINITIATORS IGM RESINS ITALIA SRL (IT) 2026-05-06 EP disclosed
US-11834532-B2 Photoinitiators IGH RESINS ITALIA S.R.L. (IT) 2023-12-05 US disclosed
CN-113518805-B Photoinitiator 意大利艾坚蒙树脂有限公司 2023-08-08 CN disclosed
US-20220098333-A1 PHOTOINITIATORS IGM RESINS ITALIA S.R.L. (IT) 2022-03-31 US disclosed
CN-113518805-A Photoinitiator 意大利艾坚蒙树脂有限公司 2021-10-19 CN disclosed
CN-103613478-B Synthetic method of alpha-hydroxyl carbonyl compound UNIV BEIJING 2015-05-06 CN disclosed
CN-103613478-A Synthetic method of alpha-hydroxyl carbonyl compound UNIV BEIJING 2014-03-05 CN disclosed
US-6287749-B1 FOR UNSATURATED COMPOUNDS FIRST CHEMICAL CORPORATION 2001-09-11 US disclosed
EP-0980393-A1 BIRADICAL PHOTOINITIATORS First Chemical Corporation (US) 2000-02-23 EP disclosed
WO-1998050437-A1 BIRADICAL PHOTOINITIATORS FIRST CHEMICAL CORPORATION (US) 1998-11-12 WO disclosed
US-4510321-A Autoxidative cleavage of ketones in the presence of pulverized alkali metal hydroxide ALLIED CORPORATION (US) 1985-04-09 US disclosed
EP-0003002-B1 USE OF AROMATIC-ALIPHATIC KETONES AS PHOTOINITIATORS, PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH KETONES AND AROMATIC-ALIPHATIC KETONES CIBA-GEIGY AG (CH) 1984-06-13 EP disclosed
US-4321118-A Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition CIBA-GEIGY CORPORATION (US) 1982-03-23 US disclosed
US-4315807-A Sensitizers for photopolymerization CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4308400-A AROMATIC HYDROXY KETONES CIBA-GEIGY A.G. (CH) 1981-12-29 US disclosed
EP-0003002-A2 Use of aromatic-aliphatic ketones as photoinitiators, photopolymerisable systems containing such ketones and aromatic-aliphatic ketones CIBA-GEIGY AG (CH) 1979-07-11 EP disclosed