Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071584 | 0.81 | MEN1 (0.39) | TSHRMEN1POLBKMT2AC5AR1 | |
| SCHEMBL11066779 | 0.81 | TSHR (0.36) | TSHRMEN1POLBKMT2AC5AR1 | |
| SCHEMBL11071524 | 0.79 | OPRM1 (0.42) | TSHR | |
| SCHEMBL11079248 | 0.78 | SLC6A4 (0.36) | TSHRMEN1POLBKMT2A | |
| SCHEMBL11078728 | 0.78 | TSHR (0.35) | TSHRMEN1POLBKMT2ANPC1 | |
| SCHEMBL11072624 | 0.77 | TSHR (0.35) | TSHRMEN1POLBKMT2A | |
| SCHEMBL11071790 | 0.77 | TSHR (0.36) | TSHRMEN1POLBKMT2A | |
| SCHEMBL11066917 | 0.77 | HTT (0.36) | TSHRTP53MEN1POLBKMT2A | |
| SCHEMBL11075481 | 0.76 | OPRM1 (0.38) | TSHRMEN1KMT2A | |
| SCHEMBL11071936 | 0.75 | SLC6A4 (0.39) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |