Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071524 | 0.88 | OPRM1 (0.42) | SLC6A4SLC6A3TSHR | |
| SCHEMBL11066779 | 0.88 | TSHR (0.36) | SLC6A4SLC6A3TSHRALDH1A1MEN1 | |
| SCHEMBL11078728 | 0.88 | TSHR (0.35) | SLC6A4SLC6A3TSHRMAPTMEN1 | |
| SCHEMBL11066917 | 0.86 | HTT (0.36) | SLC6A4SLC6A3TSHRMAPTALDH1A1 | |
| SCHEMBL11075481 | 0.85 | OPRM1 (0.38) | SLC6A4TSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL11072624 | 0.84 | TSHR (0.35) | SLC6A4SLC6A3TSHRMAPTMEN1 | |
| SCHEMBL11071790 | 0.84 | TSHR (0.36) | SLC6A4SLC6A3TSHRMAPTALDH1A1 | |
| SCHEMBL11069371 | 0.83 | TSHR (0.35) | SLC6A4SLC6A3TSHRMAPTALDH1A1 | |
| SCHEMBL11071655 | 0.82 | SLC6A4 (0.53) | SLC6A4SLC6A3TSHRMAPTALDH1A1 | |
| SCHEMBL11068867 | 0.82 | CRHR1 (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |