Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.61 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.61 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | AKT1 | P31749 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312430 | 1.00 | ALDH1A1 (0.68) | ALDH1A1MAPTKMT2ALMNANPSR1 | |
| SCHEMBL312429 | 1.00 | ALDH1A1 (0.68) | ALDH1A1MAPTKMT2ALMNANPSR1 | |
| SCHEMBL10876318 | 0.98 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2ALMNANPSR1 | |
| Formic Acid SCHEMBL3315659 | 0.93 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2ALMNANPSR1 | |
| SCHEMBL2954324 | 0.92 | MAPT (0.70) | ALDH1A1MAPTKMT2ALMNANPSR1 | |
| SCHEMBL2954318 | 0.92 | MAPT (0.70) | ALDH1A1MAPTKMT2ALMNANPSR1 | |
| SCHEMBL11073619 | 0.92 | MAPT (0.70) | ALDH1A1MAPTKMT2ALMNANPSR1 | |
| SCHEMBL14124718 | 0.87 | MAPT (0.64) | ALDH1A1MAPTKMT2ALMNANPSR1 | |
| SCHEMBL6947073 | 0.87 | MAPT (0.64) | ALDH1A1MAPTKMT2ALMNANPSR1 | |
| SCHEMBL14124738 | 0.87 | MAPT (0.64) | ALDH1A1MAPTKMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204286-B1 | PROCESS FOR PREPARING TRANS-BETA-BENZOYLACRYLIC ACID ESTER | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | claimed |
| EP-0190687-B1 | PROCESS FOR PREPARING ETHYL-ALPHA-(1-CARBOXYETHYL)-AMINO-GAMMA-OXO-GAMMA-PHENYLBUTYRATE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-10-05 | — | — | EP | claimed |
| EP-0204286-A2 | Process for preparing trans-beta-benzoylacrylic acid ester | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-12-10 | — | — | EP | claimed |
| US-7691889-B2 | Antimycobacterial compounds | LUPIN LIMITED (IN) | 2010-04-06 | — | — | US | disclosed |
| US-20070191365-A1 | 3,4,6-Substituted pyridazines for treating neuropathic pain and associated syndromes | AVIGEN, INC. | 2007-08-16 | — | — | US | disclosed |
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-20050176994-A1 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | SANKIO CHEMICAL CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1505054-A1 | PROCESS FOR PRODUCING 4-PHENYL-4-OXO-2-BUTENOIC ESTER DERIVATIVE | Sankio Chemical Co., Ltd. (JP) | 2005-02-09 | — | — | EP | disclosed |
| EP-0204286-B1 | PROCESS FOR PREPARING TRANS-BETA-BENZOYLACRYLIC ACID ESTER | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4994600-A | Process for preparing trans-β-benzoylacrylic acid ester | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0240338-B1 | BUTENOIC ACID DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-07-04 | — | — | EP | disclosed |
| US-4762944-A | ANTIULCER, ANTISECRETORY AGENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1988-08-09 | — | — | US | disclosed |
| EP-0240338-A1 | Butenoic acid derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1987-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191365-A1 | 3,4,6-Substituted pyridazines for treating neuropathic pain and associated syndromes | PMP22, P2RX6, OPRL1 | ALDH1A1 1551/4885MAPT 591/4885KMT2A 1981/4885 |
| US-20050176994-A1 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | HPD, PAH, CYP4A11 | ALDH1A1 1038/4885MAPT 2392/4885KMT2A 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.