SCHEMBL312429

SCHEMBL312429

O=C(O)/C=C/C(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
MAPT P10636 6/20 0.68
KMT2A Q03164 2/20 0.68
LMNA P02545 3/20 0.65
NPSR1 Q6W5P4 3/20 0.65
HPGD P15428 3/20 0.65
HTT P42858 2/20 0.65
THRB P10828 1/20 0.65
RECQL P46063 2/20 0.61
PLIN1 O60240 2/20 0.61
PLIN5 Q00G26 2/20 0.61
ABHD5 Q8WTS1 2/20 0.61
MAOB P27338 2/20 0.61
BCHE P06276 1/20 0.61
TNFRSF1A P19438 1/20 0.61
ACHE P22303 1/20 0.61
CYP1B1 Q16678 1/20 0.61
MAPK1 P28482 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
AKT1 P31749 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312430 1.00 ALDH1A1 (0.68) ALDH1A1MAPTKMT2ALMNANPSR1
SCHEMBL5585936 1.00 ALDH1A1 (0.68) ALDH1A1MAPTKMT2ALMNANPSR1
SCHEMBL10876318 0.98 ALDH1A1 (0.65) ALDH1A1MAPTKMT2ALMNANPSR1
Formic Acid SCHEMBL3315659 0.93 ALDH1A1 (0.61) ALDH1A1MAPTKMT2ALMNANPSR1
SCHEMBL2954324 0.92 MAPT (0.70) ALDH1A1MAPTKMT2ALMNANPSR1
SCHEMBL2954318 0.92 MAPT (0.70) ALDH1A1MAPTKMT2ALMNANPSR1
SCHEMBL11073619 0.92 MAPT (0.70) ALDH1A1MAPTKMT2ALMNANPSR1
SCHEMBL14124718 0.87 MAPT (0.64) ALDH1A1MAPTKMT2ALMNANPSR1
SCHEMBL6947073 0.87 MAPT (0.64) ALDH1A1MAPTKMT2ALMNANPSR1
SCHEMBL14124738 0.87 MAPT (0.64) ALDH1A1MAPTKMT2ALMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325548-A1 TUMOR SUPPRESSOR P73 TRANSCRIPTIONALLY REGULATES C-FLIP TO IMPEDE ITS PRIMING OF EXTRINSIC APOPTOSIS WHILE AN EXAMPLE SWITCHER COMPOUND CB-7587351 DEGRADES C-FLIP PROTEIN UNIV BROWN (US) 2025-10-23 US claimed
CN-117309712-B Rock debris porosity and connectivity rate measurement method based on magnetic nanoparticles 中国科学院地质与地球物理研究所 2025-05-13 CN claimed
US-20240093005-A1 POLYMER-COATED NANOPARTICLES, COMPOSITE NANO-EMULSION AND MACRO-EMULSION INSTITUTE OF GEOLOGY AND GEOPHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2024-03-21 US claimed
CN-117309712-A Rock debris porosity and connectivity rate measurement method based on magnetic nanoparticles 中国科学院地质与地球物理研究所 2023-12-29 CN claimed
CN-111527160-B Coating composition for galvanized steel sheet containing magnesium and steel sheet coated with the composition 浦项股份有限公司 2023-08-18 CN claimed
CN-114907576-A Polymer-coated nano-particles, composite nano-emulsion and macro-emulsion 中国科学院地质与地球物理研究所 2022-08-16 CN claimed
CN-113755059-A Photosensitive resin-based conductive ink and preparation method and application thereof 深圳大学 2021-12-07 CN claimed
CN-109437643-B Method for preparing gel reducing agent from amphoteric polyester polycarboxylic acid compound 湖北工业大学 2021-03-02 CN claimed
CN-112279954-A Polyacrylate dispersant containing multiple functional groups and preparation method thereof 广东中联邦精细化工有限公司 2021-01-29 CN claimed
CN-107924124-B Negative photoresist composition for I-line with excellent etching resistance 荣昌化学制品株式会社 2020-12-15 CN claimed
WO-1997017316-A1 4-PHENYL-4-OXO-2-BUTENOIC ACID DERIVATIVES WITH KYNURENINE-3-HYDROXYLASE INHIBITING ACTIVITY PHARMACIA & UPJOHN S.P.A. (IT) 1997-05-15 WO claimed
CN-1094027-A The benzoyl-acrylic acid di-esters contains their pharmaceutical composition and prepares their method RICHTER GEDEON VEGYESZET (HU) 1994-10-26 CN claimed
EP-0309262-B1 Novel salicylates, their salts, pharmaceutical compositions containing them and process for preparing same RICHTER GEDEON VEGYESZET (HU) 1994-02-02 EP claimed
EP-0204286-B1 PROCESS FOR PREPARING TRANS-BETA-BENZOYLACRYLIC ACID ESTER KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-12-11 EP claimed
EP-0239062-B1 N2-(1-CARBOXY-3-OXO-3-PHENYLPROPYL)-L-LYSINE COMPOUNDS AND THEIR DERIVATIVES KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-05-29 EP claimed
US-4994600-A Process for preparing trans-β-benzoylacrylic acid ester KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-02-19 US claimed
EP-0190687-B1 PROCESS FOR PREPARING ETHYL-ALPHA-(1-CARBOXYETHYL)-AMINO-GAMMA-OXO-GAMMA-PHENYLBUTYRATE KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-10-05 EP claimed
EP-0239062-A2 N2-(1-carboxy-3-oxo-3-phenylpropyl)-L-Lysine compounds and their derivatives KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-09-30 EP claimed
EP-0204286-A2 Process for preparing trans-beta-benzoylacrylic acid ester KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-12-10 EP claimed
US-4483868-A ANTIULCER AGENTS ANTISECRETORY AGENTS ROUSSEL UCLAF (FR) 1984-11-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325548-A1 TUMOR SUPPRESSOR P73 TRANSCRIPTIONALLY REGULATES C-FLIP TO IMPEDE ITS PRIMING OF EXTRINSIC APOPTOSIS WHILE AN EXAMPLE SWITCHER COMPOUND CB-7587351 DEGRADES C-FLIP PROTEIN BCOR, CCAR2, CEBPZ ALDH1A1 3993/4885MAPT 4116/4885KMT2A 2079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.