SCHEMBL25174147

SCHEMBL25174147

CCNc1cccc(C(=O)OC)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.59
EGFR P00533 1/20 0.59
MAPK1 P28482 1/20 0.59
HSD17B10 Q99714 1/20 0.59
POLB P06746 1/20 0.59
ALDH1A1 P00352 2/20 0.58
NPC1 O15118 3/20 0.56
LOXL2 Q9Y4K0 1/20 0.54
MAPT P10636 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TP53 P04637 1/20 0.54
HPGD P15428 1/20 0.54
CYP4F2 P78329 1/20 0.53
CYP4A11 Q02928 1/20 0.53
MEN1 O00255 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30445248 1.00 RAB9A (0.59) RAB9AEGFRMAPK1HSD17B10POLB
SCHEMBL3092388 0.87 KMT2A (0.63) RAB9AMAPK1HSD17B10POLBALDH1A1
SCHEMBL23518403 0.85 RAB9A (0.59) RAB9AEGFRMAPK1HSD17B10POLB
SCHEMBL25933608 0.84 HTR7 (0.58) RAB9AEGFRMAPK1HSD17B10POLB
SCHEMBL7504783 0.84 ALDH1A1 (0.49) RAB9AEGFRMAPK1HSD17B10POLB
SCHEMBL134016 0.83 EGFR (0.57) RAB9AEGFRMAPK1HSD17B10POLB
SCHEMBL8672958 0.83 RAB9A (0.60) RAB9AEGFRMAPK1HSD17B10POLB
SCHEMBL27616133 0.83 CYP4F2 (0.58) RAB9AEGFRMAPK1HSD17B10POLB
SCHEMBL7150993 0.83 HTR7 (0.57) RAB9AEGFRMAPK1HSD17B10POLB
SCHEMBL29035718 0.83 RAB9A (0.45) RAB9AEGFRMAPK1HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120285-A Heterocyclic compound, preparation method and application thereof 武汉人福创新药物研发中心有限公司 2023-05-16 CN disclosed
WO-2023078461-A1 HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 武汉人福创新药物研发中心有限公司 2023-05-11 WO disclosed
WO-2023078461-A1 HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 武汉人福创新药物研发中心有限公司 2023-05-11 WO disclosed
CN-110621766-B Dispersant, method of manufacture and use thereof 雪佛龙奥伦耐有限责任公司 2021-12-24 CN disclosed
CN-110621766-A Dispersant, method of manufacture and use thereof 雪佛龙奥伦耐有限责任公司 2019-12-27 CN disclosed