SCHEMBL11074121

SCHEMBL11074121

CCN(CCCc1ccc(Cl)cc1)c1ccc(C(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.51
CNR1 P21554 1/20 0.51
RARB P10826 6/20 0.50
ALDH1A1 P00352 4/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
LMNA P02545 2/20 0.48
POLB P06746 2/20 0.48
CTRC Q99895 1/20 0.48
MAPT P10636 3/20 0.48
RARA P10276 1/20 0.48
MTOR P42345 1/20 0.48
TSHR P16473 2/20 0.47
ALOX15 P16050 1/20 0.47
ESRRG P62508 1/20 0.46
GMNN O75496 1/20 0.46
CYP2D6 P10635 1/20 0.46
GABRA1 P14867 1/20 0.46
NFKB1 P19838 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11078927 0.91 ALDH1A1 (0.54) RARBALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL11077889 0.83 CHRM1 (0.52) RARBALDH1A1MEN1KMT2APOLB
SCHEMBL9339404 0.83 TP53 (0.52) RARBTSHRHTT
SCHEMBL24835159 0.80 NR1H2 (0.51) RARBALDH1A1MEN1KMT2AMAPT
SCHEMBL6484606 0.78 RARB (0.50) CNR1RARBALDH1A1MEN1KMT2A
SCHEMBL1348794 0.77 RARB (0.60) RARBALDH1A1MEN1KMT2ALMNA
SCHEMBL7471413 0.77 EGFR (0.58) RARBALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL5536365 0.77 CNR2 (0.44) CNR2CNR1MEN1KMT2ASMN1; SMN2
SCHEMBL64440 0.77 MEN1 (0.56) CNR2RARBALDH1A1MEN1KMT2A
SCHEMBL5751057 0.77 TSHR (0.74) RARBALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4489094-A Arylalkylaminobenzoic acids AMERICAN CYANAMID COMPANY (US) 1984-12-18 US disclosed