Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 6/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078927 | 0.85 | ALDH1A1 (0.54) | ALDH1A1ALOX15TSHRRARBMEN1 | |
| SCHEMBL10373059 | 0.83 | RXRA (0.58) | ALDH1A1ALOX15TSHRMEN1KMT2A | |
| SCHEMBL11074121 | 0.83 | CNR2 (0.51) | ALDH1A1ALOX15TSHRRARBMEN1 | |
| SCHEMBL9339110 | 0.82 | NR4A2 (0.54) | ALDH1A1ALOX15TSHRRARBNR4A2 | |
| SCHEMBL1346949 | 0.79 | RARB (0.59) | ALDH1A1RARBMEN1KMT2ARARA | |
| SCHEMBL5751057 | 0.79 | TSHR (0.74) | ALDH1A1ALOX15TSHRRARBMEN1 | |
| SCHEMBL27747274 | 0.78 | PPARG (0.50) | ALDH1A1RARBMEN1KMT2APOLB | |
| SCHEMBL14207379 | 0.78 | MEN1 (0.46) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL9458908 | 0.78 | MAPT (0.54) | ALDH1A1TSHRRARBMEN1KMT2A | |
| SCHEMBL29114273 | 0.76 | PTGES (0.51) | ALDH1A1TSHRRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489094-A | Arylalkylaminobenzoic acids | AMERICAN CYANAMID COMPANY (US) | 1984-12-18 | — | — | US | disclosed |