Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | GLA | P06280 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071937 | 0.88 | KDM4E (0.51) | KMT2AKDM4EMAPK1MAPTHSD17B10 | |
| SCHEMBL11098613 | 0.85 | KDM4E (0.50) | KMT2AKDM4EMAPK1MAPTHSD17B10 | |
| SCHEMBL11098611 | 0.74 | KDM4E (0.56) | KDM4EMAPK1MAPTHSD17B10HPGD | |
| SCHEMBL10038083 | 0.70 | NFKB1 (0.66) | KMT2AKDM4EMAPK1MAPTHSD17B10 | |
| SCHEMBL31036841 | 0.69 | NFKB1 (0.52) | KMT2AKDM4EMAPK1MAPTHSD17B10 | |
| SCHEMBL11071263 | 0.68 | KDM4E (0.41) | KMT2AKDM4EMAPK1MAPTHSD17B10 | |
| SCHEMBL9204717 | 0.68 | MAOB (0.46) | KMT2AKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL6545788 | 0.68 | MAOB (0.60) | KMT2AKDM4EHPGDGAAGLA | |
| SCHEMBL23657887 | 0.67 | KDM4E (0.74) | KMT2AKDM4EMAPK1MAPTHSD17B10 | |
| SCHEMBL6545797 | 0.67 | MAOB (0.58) | KMT2AKDM4EHSD17B10HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |