Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071937 | 0.88 | KDM4E (0.51) | KDM4EHSD17B10MAPTMAPK1GLA | |
| SCHEMBL11074157 | 0.85 | KMT2A (0.57) | KDM4EHSD17B10MAPTMAPK1GLA | |
| SCHEMBL11098611 | 0.80 | KDM4E (0.56) | KDM4EHSD17B10MAPTMAPK1GLA | |
| SCHEMBL11077944 | 0.77 | KDM4E (0.52) | KDM4EHSD17B10MAPTGLACYP1A2 | |
| SCHEMBL11071263 | 0.76 | KDM4E (0.41) | KDM4EHSD17B10MAPTMAPK1GLA | |
| SCHEMBL11081738 | 0.75 | KDM4E (0.49) | KDM4EHSD17B10MAPTMAPK1GLA | |
| SCHEMBL6036796 | 0.72 | KDM4E (0.52) | KDM4EHSD17B10MAPTMAPK1ALDH1A1 | |
| SCHEMBL11066772 | 0.71 | LMNA (0.41) | KDM4EHSD17B10MAPTMAPK1GLA | |
| SCHEMBL23657887 | 0.70 | KDM4E (0.74) | KDM4EHSD17B10MAPTMAPK1GLA | |
| SCHEMBL1865302 | 0.70 | KDM4E (0.66) | KDM4EHSD17B10MAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |