Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081453 | 0.78 | OPRM1 (0.43) | OPRM1SLC6A4DRD3OPRK1OPRD1 | |
| SCHEMBL11089351 | 0.78 | DRD3 (0.43) | OPRM1DRD3OPRK1OPRD1 | |
| SCHEMBL11093324 | 0.77 | DRD3 (0.45) | OPRM1DRD3OPRK1OPRD1 | |
| SCHEMBL11069621 | 0.77 | OPRL1 (0.43) | DRD3HTR1ADRD1DRD4DRD5 | |
| SCHEMBL11079594 | 0.77 | DRD3 (0.44) | OPRM1DRD3OPRD1HTR1ADRD1 | |
| SCHEMBL11079139 | 0.76 | DRD3 (0.42) | OPRM1DRD3OPRD1HTR1ADRD1 | |
| SCHEMBL11069660 | 0.74 | OPRM1 (0.46) | OPRM1DRD3OPRK1OPRD1 | |
| SCHEMBL11076282 | 0.74 | OPRM1 (0.41) | OPRM1SLC6A4OPRK1OPRD1SLC6A2 | |
| SCHEMBL11094533 | 0.74 | DRD3 (0.41) | OPRM1SLC6A4DRD3 | |
| Morpholine SCHEMBL11066057 | 0.74 | GRIN2D (0.41) | OPRM1SLC6A4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |