Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093324 | 0.99 | DRD3 (0.45) | DRD3OPRM1OPRK1OPRD1 | |
| SCHEMBL11094533 | 0.96 | DRD3 (0.41) | DRD3OPRM1 | |
| Ethylene SCHEMBL11093778 | 0.94 | DRD3 (0.40) | DRD3OPRM1 | |
| SCHEMBL11557919 | 0.91 | DRD3 (0.38) | DRD3OPRM1OPRD1 | |
| SCHEMBL11092102 | 0.84 | GRIN2D (0.36) | — | |
| SCHEMBL11090461 | 0.82 | CTSD (0.38) | OPRM1OPRK1OPRD1 | |
| Hydrochloric Acid SCHEMBL11099779 | 0.81 | ALDH1A1 (0.37) | — | |
| SCHEMBL11097718 | 0.81 | ALDH1A1 (0.37) | — | |
| SCHEMBL11096535 | 0.80 | OPRM1 (0.43) | OPRM1OPRK1OPRD1 | |
| SCHEMBL11069466 | 0.80 | ALOX5 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |