Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL11077014 | 0.99 | GRIN2D (0.43) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| Morpholine SCHEMBL11069454 | 0.80 | DRD2 (0.36) | DRD3SLC6A4OPRM1 | |
| SCHEMBL11069621 | 0.77 | OPRL1 (0.43) | DRD3 | |
| Morpholine SCHEMBL11643273 | 0.77 | OPRM1 (0.45) | SLC6A4OPRM1 | |
| SCHEMBL11089351 | 0.76 | DRD3 (0.43) | DRD3OPRM1 | |
| SCHEMBL11093324 | 0.75 | DRD3 (0.45) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| Morpholine SCHEMBL11073425 | 0.74 | SLC6A4 (0.39) | SLC6A4OPRM1 | |
| SCHEMBL11074291 | 0.74 | OPRM1 (0.39) | DRD3SLC6A4OPRM1 | |
| Morpholine SCHEMBL11079848 | 0.73 | OPRM1 (0.41) | DRD3SLC6A4OPRM1 | |
| Eticyclidine SCHEMBL29055231 | 0.73 | GRIN2D (0.45) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |